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Genetic variants in nuclear DNA along with environmental factors modify mitochondrial DNA copy number: a population-based exome-wide association study

BACKGROUND: Mitochondrial DNA (mtDNA) copy number has been found associated with multiple diseases, including cancers, diabetes and so on. Both environmental and genetic factors could affect the copy number of mtDNA. However, limited study was available about the relationship between genetic variant...

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Publicado en:BMC Genomics
Main Authors: Li, Zhihua, Zhu, Meng, Du, Jiangbo, Ma, Hongxia, Jin, Guangfu, Dai, Juncheng
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192277/
https://ncbi.nlm.nih.gov/pubmed/30326835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5142-7
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