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Diverse target gene modifications in Plasmodium falciparum using Bxb1 integrase and an intronic attB

Genetic manipulation of the human malaria parasite Plasmodium falciparum is needed to explore pathogen biology and evaluate antimalarial targets. It is, however, aggravated by a low transfection efficiency, a paucity of selectable markers and a biased A/T-rich genome. While various enabling technolo...

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Bibliografske podrobnosti
izdano v:Parasit Vectors
Main Authors: Balabaskaran-Nina, Praveen, Desai, Sanjay A.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192176/
https://ncbi.nlm.nih.gov/pubmed/30333047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-018-3129-5
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