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Population Pharmacokinetics of Darbepoetin in Infants Following Single Intravenous and Subcutaneous Dosing

Darbepoetin alfa (Darbe) is a hyperglycosylated analogue of recombinant human erythropoietin (Epo). The aim of this study was to develop a population pharmacokinetic model for Darbe following intravenous (i.v.) and subcutaneous (s.c.) administration to infants. Data from 2 infant clinical studies (a...

詳細記述

保存先:
書誌詳細
出版年:J Pharm Sci
主要な著者: An, Guohua, Ohls, Robin K., Christensen, Robert D., Widness, John A., Mock, Donald M., Veng-Pedersen, Peter
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190690/
https://ncbi.nlm.nih.gov/pubmed/28189627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.02.001
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