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Population Pharmacokinetics of Darbepoetin in Infants Following Single Intravenous and Subcutaneous Dosing
Darbepoetin alfa (Darbe) is a hyperglycosylated analogue of recombinant human erythropoietin (Epo). The aim of this study was to develop a population pharmacokinetic model for Darbe following intravenous (i.v.) and subcutaneous (s.c.) administration to infants. Data from 2 infant clinical studies (a...
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| Udgivet i: | J Pharm Sci |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6190690/ https://ncbi.nlm.nih.gov/pubmed/28189627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.02.001 |
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