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Population Pharmacokinetics of Darbepoetin in Infants Following Single Intravenous and Subcutaneous Dosing

Darbepoetin alfa (Darbe) is a hyperglycosylated analogue of recombinant human erythropoietin (Epo). The aim of this study was to develop a population pharmacokinetic model for Darbe following intravenous (i.v.) and subcutaneous (s.c.) administration to infants. Data from 2 infant clinical studies (a...

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Bibliografiske detaljer
Udgivet i:J Pharm Sci
Main Authors: An, Guohua, Ohls, Robin K., Christensen, Robert D., Widness, John A., Mock, Donald M., Veng-Pedersen, Peter
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190690/
https://ncbi.nlm.nih.gov/pubmed/28189627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.02.001
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