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Differential substrate recognition by maltose binding proteins influenced by structure and dynamics

The genome of the hyperthermophile Thermotoga maritima contains three isoforms of maltose binding protein (MBP) that are high affinity receptors for di-, tri- and tetra-saccharides. Two of these proteins (tmMBP1 and tmMBP2) share significant sequence identity, approximately 90%, while the third (tmM...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Shukla, Shantanu, Bafna, Khushboo, Gullett, Caeley, Myles, Dean A. A., Agarwal, Pratul K., Cuneo, Matthew J.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189639/
https://ncbi.nlm.nih.gov/pubmed/30204415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00783
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