Using a Virion Assembly-Defective Dengue Virus as a Vaccine Approach

Dengue virus (DENV) is the most prevalent mosquito-transmitted viral pathogen in humans. The recently licensed dengue vaccine has major weaknesses. Therefore, there is an urgent need to develop improved dengue vaccines. Here, we report a virion assembly-defective DENV as a vaccine platform. DENV con...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Shan, Chao, Xie, Xuping, Zou, Jing, Züst, Roland, Zhang, Bo, Ambrose, Rebecca, Mackenzie, Jason, Fink, Katja, Shi, Pei-Yong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189489/
https://ncbi.nlm.nih.gov/pubmed/30111567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01002-18
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