Comparative Analysis of B-Cell Receptor Repertoires Induced by Live Yellow Fever Vaccine in Young and Middle-Age Donors

Age-related changes can significantly alter the state of adaptive immune system and often lead to attenuated response to novel pathogens and vaccination. In present study we employed 5′RACE UMI-based full length and nearly error-free immunoglobulin profiling to compare plasma cell antibody repertoir...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Davydov, Alexey N., Obraztsova, Anna S., Lebedin, Mikhail Y., Turchaninova, Maria A., Staroverov, Dmitriy B., Merzlyak, Ekaterina M., Sharonov, George V., Kladova, Olga, Shugay, Mikhail, Britanova, Olga V., Chudakov, Dmitriy M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189279/
https://ncbi.nlm.nih.gov/pubmed/30356675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02309
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