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C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event

Therapeutic targeting of specific genetic changes in cancer has proven to be an effective therapy and the concept of synthetic lethality has emerged. CCAAT/enhancer-binding protein-β (C/EBPβ), a basic leucine zipper transcription factor, has important roles in cellular processes including differenti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Messenger, Zachary J., Hall, Jonathan R., Jima, Dereje D., House, John S., Tam, Hann W., Tokarz, Debra A., Smart, Robert C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189130/
https://ncbi.nlm.nih.gov/pubmed/30323292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1103-y
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