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KCC2 Regulates Dendritic Spine Formation in a Brain-Region Specific and BDNF Dependent Manner

KCC2 is the major chloride extruder in neurons. The spatiotemporal regulation of KCC2 expression orchestrates the developmental shift towards inhibitory GABAergic drive and the formation of glutamatergic synapses. Whether KCC2’s role in synapse formation is similar in different brain regions is unkn...

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Vydáno v:Cereb Cortex
Hlavní autoři: Awad, Patricia Nora, Amegandjin, Clara Akofa, Szczurkowska, Joanna, Carriço, Josianne Nuñes, Fernandes do Nascimento, Antônia Samia, Baho, Elie, Chattopadhyaya, Bidisha, Cancedda, Laura, Carmant, Lionel, Di Cristo, Graziella
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188549/
https://ncbi.nlm.nih.gov/pubmed/30169756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhy198
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