Sensitive period for rescuing parvalbumin interneurons connectivity and social behavior deficits caused by TSC1 loss

The Mechanistic Target Of Rapamycin Complex 1 (mTORC1) pathway controls several aspects of neuronal development. Mutations in regulators of mTORC1, such as Tsc1 and Tsc2, lead to neurodevelopmental disorders associated with autism, intellectual disabilities and epilepsy. The correct development of i...

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Publicado en:Nat Commun
Autores principales: Amegandjin, Clara A., Choudhury, Mayukh, Jadhav, Vidya, Carriço, Josianne Nunes, Quintal, Ariane, Berryer, Martin, Snapyan, Marina, Chattopadhyaya, Bidisha, Saghatelyan, Armen, Di Cristo, Graziella
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209106/
https://ncbi.nlm.nih.gov/pubmed/34135323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23939-7
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