Peptide dendrimers as “lead compounds” for the treatment of chronic lung infections by Pseudomonas aeruginosa in cystic fibrosis patients: in vitro and in vivo studies

AIM: In the present work, the potential of the D-enantiomeric dendrimers dG3KL and dTNS18 was evaluated in relation to tobramycin (Tob), for the development of novel antibacterials to treat Pseudomonas aeruginosa chronic lung infections in patients with cystic fibrosis. RESULTS: The activity of dend...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Drug Resist
Hauptverfasser: Pompilio, Arianna, Geminiani, Cristina, Mantini, Paolo, Siriwardena, Thissa N, Di Bonaventura, Ivan, Reymond, Jean Louis, Di Bonaventura, Giovanni
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2018
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188189/
https://ncbi.nlm.nih.gov/pubmed/30349334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S168868
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