Peptide dendrimers as “lead compounds” for the treatment of chronic lung infections by Pseudomonas aeruginosa in cystic fibrosis patients: in vitro and in vivo studies

AIM: In the present work, the potential of the D-enantiomeric dendrimers dG3KL and dTNS18 was evaluated in relation to tobramycin (Tob), for the development of novel antibacterials to treat Pseudomonas aeruginosa chronic lung infections in patients with cystic fibrosis. RESULTS: The activity of dend...

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Publicado en:Infect Drug Resist
Autores principales: Pompilio, Arianna, Geminiani, Cristina, Mantini, Paolo, Siriwardena, Thissa N, Di Bonaventura, Ivan, Reymond, Jean Louis, Di Bonaventura, Giovanni
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2018
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188189/
https://ncbi.nlm.nih.gov/pubmed/30349334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S168868
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