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A small molecule regulator of tissue transglutaminase conformation inhibits the malignant phenotype of cancer cells

The protein crosslinking enzyme tissue transglutaminase (tTG) is an acyltransferase which catalyzes transamidation reactions between two proteins, or between a protein and a polyamine. It is frequently overexpressed in several different types of human cancer cells, where it has been shown to contrib...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Katt, William P., Blobel, Nicolas J., Komarova, Svetlana, Antonyak, Marc A., Nakano, Ichiro, Cerione, Richard A.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188150/
https://ncbi.nlm.nih.gov/pubmed/30344949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26193
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