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A small molecule regulator of tissue transglutaminase conformation inhibits the malignant phenotype of cancer cells

The protein crosslinking enzyme tissue transglutaminase (tTG) is an acyltransferase which catalyzes transamidation reactions between two proteins, or between a protein and a polyamine. It is frequently overexpressed in several different types of human cancer cells, where it has been shown to contrib...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Katt, William P., Blobel, Nicolas J., Komarova, Svetlana, Antonyak, Marc A., Nakano, Ichiro, Cerione, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188150/
https://ncbi.nlm.nih.gov/pubmed/30344949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26193
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