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The diamond anniversary of tissue transglutaminase: a protein of many talents

Tissue transglutaminase (tTG) is capable of binding and hydrolyzing GTP, as well as catalyzing an enzymatic transamidation reaction that crosslinks primary amines to glutamine residues. tTG adopts two vastly different conformations, depending on whether it is functioning as a GTP-binding protein or...

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Bibliografische gegevens
Gepubliceerd in:Drug Discov Today
Hoofdauteurs: Katt, William P., Antonyak, Marc A., Cerione, Richard A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864117/
https://ncbi.nlm.nih.gov/pubmed/29362136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2018.01.037
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