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The diamond anniversary of tissue transglutaminase: a protein of many talents

Tissue transglutaminase (tTG) is capable of binding and hydrolyzing GTP, as well as catalyzing an enzymatic transamidation reaction that crosslinks primary amines to glutamine residues. tTG adopts two vastly different conformations, depending on whether it is functioning as a GTP-binding protein or...

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Bibliografske podrobnosti
izdano v:Drug Discov Today
Main Authors: Katt, William P., Antonyak, Marc A., Cerione, Richard A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864117/
https://ncbi.nlm.nih.gov/pubmed/29362136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2018.01.037
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