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Molecular dynamics simulation reveals the possible druggable hot-spots of USP7
The plasticity in Ubiquitin Specific Proteases (USP7) inducing conformational changes at important areas has highlighted an intricate mechanism, by which USP7 is regulated. Given the importance of USP7 in oncogenic pathways and immune-oncology, identification of USP7 inhibitors has attracted conside...
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| Udgivet i: | Oncotarget |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Impact Journals LLC
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6188144/ https://ncbi.nlm.nih.gov/pubmed/30344943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26136 |
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