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Shapeshifting RNAs guide innate immunity

The innate immune system can distinguish between RNAs of viral and cellular origin, but the basis for this discrimination is not known. A new paper by Calderon and Conn demonstrates that conformational plasticity determines the ability of one RNA sequence to bind to and activate the pattern recognit...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Glavni avtor: Dinman, Jonathan D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187635/
https://ncbi.nlm.nih.gov/pubmed/30315089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H118.005799
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