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Shapeshifting RNAs guide innate immunity

The innate immune system can distinguish between RNAs of viral and cellular origin, but the basis for this discrimination is not known. A new paper by Calderon and Conn demonstrates that conformational plasticity determines the ability of one RNA sequence to bind to and activate the pattern recognit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
1. Verfasser: Dinman, Jonathan D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187635/
https://ncbi.nlm.nih.gov/pubmed/30315089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H118.005799
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