Proteolipid domains form in biomimetic and cardiac mitochondrial vesicles and are regulated by cardiolipin concentration but not monolyso-cardiolipin

Cardiolipin (CL) is an anionic phospholipid mainly located in the inner mitochondrial membrane, where it helps regulate bioenergetics, membrane structure, and apoptosis. Localized, phase-segregated domains of CL are hypothesized to control mitochondrial inner membrane organization. However, the exis...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Pennington, Edward Ross, Sullivan, E. Madison, Fix, Amy, Dadoo, Sahil, Zeczycki, Tonya N., DeSantis, Anita, Schlattner, Uwe, Coleman, Rosalind A., Chicco, Adam J., Brown, David A., Shaikh, Saame Raza
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2018
Subjects:
Lipids
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187616/
https://ncbi.nlm.nih.gov/pubmed/30158245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004948
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