Docosahexaenoic acid lowers cardiac mitochondrial enzyme activity by replacing linoleic acid in the phospholipidome

Cardiac mitochondrial phospholipid acyl chains regulate respiratory enzymatic activity. In several diseases, the rodent cardiac phospholipidome is extensively rearranged; however, whether specific acyl chains impair respiratory enzyme function is unknown. One unique remodeling event in the myocardiu...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Sullivan, E. Madison, Pennington, Edward Ross, Sparagna, Genevieve C., Torres, Maria J., Neufer, P. Darrell, Harris, Mitchel, Washington, James, Anderson, Ethan J., Zeczycki, Tonya N., Brown, David A., Shaikh, Saame Raza
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
Soggetti:
Lipids
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767854/
https://ncbi.nlm.nih.gov/pubmed/29162722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.812834
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