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FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models

FUS (fused in sarcoma) proteinopathy is a group of neurodegenerative diseases characterized by the formation of inclusion bodies containing the FUS protein, including frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Previous studies show that mitochondrial damage is an important...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Deng, Jianwen, Wang, Peng, Chen, Xiaoping, Cheng, Haipeng, Liu, Jianghong, Fushimi, Kazuo, Zhu, Li, Wu, Jane Y.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187197/
https://ncbi.nlm.nih.gov/pubmed/30249657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806655115
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