FUS Interacts with HSP60 to Promote Mitochondrial Damage

FUS-proteinopathies, a group of heterogeneous disorders including ALS-FUS and FTLD-FUS, are characterized by the formation of inclusion bodies containing the nuclear protein FUS in the affected patients. However, the underlying molecular and cellular defects remain unclear. Here we provide evidence...

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Vydáno v:PLoS Genet
Hlavní autoři: Deng, Jianwen, Yang, Mengxue, Chen, Yanbo, Chen, Xiaoping, Liu, Jianghong, Sun, Shufeng, Cheng, Haipeng, Li, Yang, Bigio, Eileen H., Mesulam, Marsel, Xu, Qi, Du, Sidan, Fushimi, Kazuo, Zhu, Li, Wu, Jane Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559378/
https://ncbi.nlm.nih.gov/pubmed/26335776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005357
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