Single-molecule analysis of endogenous β-actin mRNA trafficking reveals a mechanism for compartmentalized mRNA localization in axons

During embryonic nervous system assembly, mRNA localization is precisely regulated in growing axons, affording subcellular autonomy by allowing controlled protein expression in space and time. Different sets of mRNAs exhibit different localization patterns across the axon. However, little is known a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Turner-Bridger, Benita, Jakobs, Maximillian, Muresan, Leila, Wong, Hovy Ho-Wai, Franze, Kristian, Harris, William A., Holt, Christine E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2018
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187124/
https://ncbi.nlm.nih.gov/pubmed/30254174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806189115
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