Single-molecule analysis of endogenous β-actin mRNA trafficking reveals a mechanism for compartmentalized mRNA localization in axons

During embryonic nervous system assembly, mRNA localization is precisely regulated in growing axons, affording subcellular autonomy by allowing controlled protein expression in space and time. Different sets of mRNAs exhibit different localization patterns across the axon. However, little is known a...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Turner-Bridger, Benita, Jakobs, Maximillian, Muresan, Leila, Wong, Hovy Ho-Wai, Franze, Kristian, Harris, William A., Holt, Christine E.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
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PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187124/
https://ncbi.nlm.nih.gov/pubmed/30254174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806189115
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