FoxO function is essential for maintenance of autophagic flux and neuronal morphogenesis in adult neurogenesis

Autophagy is a conserved catabolic pathway with emerging functions in mammalian neurodevelopment and human neurodevelopmental diseases. The mechanisms controlling autophagy in neuronal development are not fully understood. Here, we found that conditional deletion of the Forkhead Box O transcription...

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Dades bibliogràfiques
Publicat a:Neuron
Autors principals: Schäffner, Iris, Minakaki, Georgia, Khan, M. Amir, Balta, Elli-Anna, Schlötzer-Schrehardt, Ursula, Schwarz, Tobias J., Beckervordersandforth, Ruth, Winner, Beate, Webb, Ashley E., DePinho, Ronald A., Paik, Jihye, Wurst, Wolfgang, Klucken, Jochen, Lie, D. Chichung
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186958/
https://ncbi.nlm.nih.gov/pubmed/30197237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.08.017
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