FoxO function is essential for maintenance of autophagic flux and neuronal morphogenesis in adult neurogenesis

Autophagy is a conserved catabolic pathway with emerging functions in mammalian neurodevelopment and human neurodevelopmental diseases. The mechanisms controlling autophagy in neuronal development are not fully understood. Here, we found that conditional deletion of the Forkhead Box O transcription...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Schäffner, Iris, Minakaki, Georgia, Khan, M. Amir, Balta, Elli-Anna, Schlötzer-Schrehardt, Ursula, Schwarz, Tobias J., Beckervordersandforth, Ruth, Winner, Beate, Webb, Ashley E., DePinho, Ronald A., Paik, Jihye, Wurst, Wolfgang, Klucken, Jochen, Lie, D. Chichung
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186958/
https://ncbi.nlm.nih.gov/pubmed/30197237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.08.017
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