FoxO function is essential for maintenance of autophagic flux and neuronal morphogenesis in adult neurogenesis

Autophagy is a conserved catabolic pathway with emerging functions in mammalian neurodevelopment and human neurodevelopmental diseases. The mechanisms controlling autophagy in neuronal development are not fully understood. Here, we found that conditional deletion of the Forkhead Box O transcription...

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Bibliographic Details
Published in:Neuron
Main Authors: Schäffner, Iris, Minakaki, Georgia, Khan, M. Amir, Balta, Elli-Anna, Schlötzer-Schrehardt, Ursula, Schwarz, Tobias J., Beckervordersandforth, Ruth, Winner, Beate, Webb, Ashley E., DePinho, Ronald A., Paik, Jihye, Wurst, Wolfgang, Klucken, Jochen, Lie, D. Chichung
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186958/
https://ncbi.nlm.nih.gov/pubmed/30197237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.08.017
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