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Impact of Swiprosin-1/Efhd2 on Adult Hippocampal Neurogenesis

Swiprosin-1/Efhd2 (Efhd2) is highly expressed in the CNS during development and in the adult. EFHD2 is regulated by Ca(2+) binding, stabilizes F-actin, and promotes neurite extension. Previous studies indicated a dysregulation of EFHD2 in human Alzheimer's disease brains. We hypothesized a detr...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Regensburger, Martin, Prots, Iryna, Reimer, Dorothea, Brachs, Sebastian, Loskarn, Sandra, Lie, Dieter Chichung, Mielenz, Dirk, Winner, Beate
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830914/
https://ncbi.nlm.nih.gov/pubmed/29337116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.12.010
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