AB083. TEW-7197, a novel orally bioavailable activin receptor-like kinase 5 inhibitor, promotes regression of fibrotic plaque in a rat model of Peyronie’s disease

BACKGROUND: To examine therapeutic effect of TEW-7197, a novel small molecule inhibitor of activin receptor-like kinase 5 (ALK5), in an animal model of Peyronie’s disease (PD) and to determine mechanisms by which TEW-7197 ameliorates fibrotic responses in primary fibroblasts derived from human PD pl...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Transl Androl Urol
Hlavní autoři: Song, Kang-Moon, Choi, Min Ji, Ghatak, Kalyan, Minh, Nguyen Nhat, Kwon, Mi-Hye, Ock, Jiyeon, Yin, Guo Nan, Ryu, Ji-Kan, Suh, Jun-Kyu
Médium: Artigo
Jazyk:Inglês
Vydáno: AME Publishing Company 2018
Témata:
Printed Abstract
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186741/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau.2018.AB083
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky