AB088. Inhibition of prongf pathway restores erectile function through dual angiogenic and neurotrophic effects in the diabetic mouse

BACKGROUND: Patients with diabetic erectile dysfunction (ED) usually respond poorly to oral phosphodiesterase-5 inhibitors due to a lack of bioavailable nitric oxide from severe endothelial and neural dysfunction. ProNGF and its receptor p75(NTR) are known to be up-regulated in diabetic condition an...

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Published in:Transl Androl Urol
Main Authors: Minh, Nguyen Nhat, Song, Kang-Moon, Choi, Min-Ji, Ghatak, Kalyan, Kwon, Mi-Hye, Yin, Guo Nan, Ryu, Ji-Kan, Suh, Jun-Kyu
Format: Artigo
Language:Inglês
Published: AME Publishing Company 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186664/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau.2018.AB088
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