Blocking ‘don’t eat me’ signal of CD47-SIRPα in hematological malignancies, an in-depth review

Hematological malignancies express high levels of CD47 as a mechanism of immune evasion. CD47-SIRPα triggers a cascade of events that inhibit phagocytosis. Preclinical research supports several models of antibody-mediated blockade of CD47-SIRPα resulting in cell death signaling, phagocytosis of cell...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Blood Rev
Hlavní autoři: Russ, Atlantis, Hua, Anh B., Montfort, William R., Rahman, Bushra, Riaz, Irbaz Bin, Khalid, Muhammad Umar, Carew, Jennifer S., Nawrocki, Steffan T., Persky, Daniel, Anwer, Faiz
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186508/
https://ncbi.nlm.nih.gov/pubmed/29709247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.blre.2018.04.005
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky