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Nanodisc-Forming Scaffold Protein Promoted Retardation of Amyloid-beta Aggregation
Peptidic-nanodiscs are useful membrane-mimetic tools for structural and functional studies of membrane proteins, and membrane interacting peptides including amyloids. Here, we demonstrate anti-amyloidogenic activities of a nanodisc-forming 18-residue peptide (denoted as 4F), both in lipid-bound and...
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| Publié dans: | J Mol Biol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6186505/ https://ncbi.nlm.nih.gov/pubmed/30170005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.08.018 |
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