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MicroRNA binding mediated Functional sequence variant in 3′-UTR of DNA repair Gene XPC in Age-related Cataract

DNA oxidative damage repair is strongly involved in the pathogenesis of age-related cataract (ARC). The sequence variants of in coding region of DNA repair genes have been shown to be associated with ARC. It is known that single nucleotide polymorphisms (SNPs) in the 3′-terminal untranslated region...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zou, Xi, Kang, Lihua, Yang, Mei, Wu, Jian, Guan, Huaijin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6185952/
https://ncbi.nlm.nih.gov/pubmed/30315181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33071-0
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