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Epigenetic Regulation of Werner Syndrome Gene in Age-Related Cataract

Purpose. To examine the promoter methylation and histone modification of WRN (Werner syndrome gene), a DNA repair gene, and their relationship with the gene expression in age-related cataract (ARC) lens. Methods. We collected the lenses after cataract surgery from 117ARC patients and 39 age-matched...

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Huvudupphovsmän: Xi Zhu, Guowei Zhang, Lihua Kang, Huaijin Guan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Limited 2015-01-01
Serie:Journal of Ophthalmology
Länkar:http://dx.doi.org/10.1155/2015/579695
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