POH1 deubiquitinates pro-interleukin-1β and restricts inflammasome activity

Inflammasome activation is essential for host defence against invading pathogens, but is also involved in various forms of inflammatory diseases. The processes that control inflammasome activity are thus important for averting excessive immune responses and tissue damage. Here we show that the deubi...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhang, Li, Liu, Yun, Wang, Boshi, Xu, Guiqin, Yang, Zhaojuan, Tang, Ming, Ma, Aihui, Jing, Tiantian, Xu, Xiaoli, Zhang, Xiaoren, Liu, Yongzhong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6185913/
https://ncbi.nlm.nih.gov/pubmed/30315153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06455-z
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