POH1 deubiquitinates pro-interleukin-1β and restricts inflammasome activity

Inflammasome activation is essential for host defence against invading pathogens, but is also involved in various forms of inflammatory diseases. The processes that control inflammasome activity are thus important for averting excessive immune responses and tissue damage. Here we show that the deubi...

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Vydáno v:Nat Commun
Hlavní autoři: Zhang, Li, Liu, Yun, Wang, Boshi, Xu, Guiqin, Yang, Zhaojuan, Tang, Ming, Ma, Aihui, Jing, Tiantian, Xu, Xiaoli, Zhang, Xiaoren, Liu, Yongzhong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6185913/
https://ncbi.nlm.nih.gov/pubmed/30315153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06455-z
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