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EFFECTS OF PHARMACOLOGICAL INHIBITION OF AGING-ASSOCIATED PATHWAYS OF DROSOPHILA LIFESPAN
Mutations of the PI3K, TOR, iNOS, and NF-κB genes increase lifespan of model organisms and reduce the risk of some aging-associated diseases. We studied the effects of inhibitors of PI3K (wortmannin), TOR (rapamycin), iNOS (1400W), NF-κB (pyrrolidin dithiocarbamate and QNZ), and the combined effects...
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| Publicat a: | Innov Aging |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6184813/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.3082 |
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