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INDY REDUCTION PRESERVES FLY HEALTH AND HOMEOSTASIS
Indy (I’m not dead yet) encodes the fly homolog of a mammalian mIndy (SLC13A5) plasma membrane citrate transporter. Reduction of Indy gene activity in flies, or its homolog in worm extends longevity. Decreased expression of INDY in flies, worms, rats, and mice has beneficial effects on energy balanc...
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| Udgivet i: | Innov Aging |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6184567/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.3088 |
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