INDY REDUCTION PRESERVES FLY HEALTH AND HOMEOSTASIS

Indy (I’m not dead yet) encodes the fly homolog of a mammalian mIndy (SLC13A5) plasma membrane citrate transporter. Reduction of Indy gene activity in flies, or its homolog in worm extends longevity. Decreased expression of INDY in flies, worms, rats, and mice has beneficial effects on energy balanc...

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Bibliographic Details
Published in:Innov Aging
Main Authors: Rogina, B., Rogers, R.P., Woods, J.K., Chung, M.S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6184567/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.3088
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