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INDY REDUCTION PRESERVES FLY HEALTH AND HOMEOSTASIS

Indy (I’m not dead yet) encodes the fly homolog of a mammalian mIndy (SLC13A5) plasma membrane citrate transporter. Reduction of Indy gene activity in flies, or its homolog in worm extends longevity. Decreased expression of INDY in flies, worms, rats, and mice has beneficial effects on energy balanc...

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Foilsithe in:Innov Aging
Main Authors: Rogina, B., Rogers, R.P., Woods, J.K., Chung, M.S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6184567/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.3088
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