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MITOCHONDRIAL DNA HETEROPLASMY LEADS TO AGE-RELATED FUNCTIONAL DECLINE AND INCREASED MORTALITY RISK
Mitochondrial DNA (mtDNA) heteroplasmy is a measure of relative levels of mutated and normal mtDNA molecules in a cell. High levels of heteroplasmy at specific mtDNA sites causes inherited mitochondrial diseases with neurological, sensory, metabolic, cardiovascular, and movement impairments. Here we...
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| Publicat a: | Innov Aging |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6184556/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.3089 |
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