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P49/STRAP TARGETS PGC-1 GENE AND MODULATES MITOCHONDRIAL FUNCTION IN AGING

Introduction: p49/STRAP (SRFBP1) is a serum response factor (SRF) binding protein, which regulates many genes. p49/STRAP has a SRF binding domain and a BUD22 domain (which modulates growth and cell size). In addition, p49/STRAP alters the intracellular NAD/NADH ratio and induces protein deacetylatio...

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Bibliografiske detaljer
Udgivet i:Innov Aging
Main Authors: Zhang, X., Azhar, G., Rogers, S., Wei, J.Y.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6183432/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.4436
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