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P49/STRAP TARGETS PGC-1 GENE AND MODULATES MITOCHONDRIAL FUNCTION IN AGING
Introduction: p49/STRAP (SRFBP1) is a serum response factor (SRF) binding protein, which regulates many genes. p49/STRAP has a SRF binding domain and a BUD22 domain (which modulates growth and cell size). In addition, p49/STRAP alters the intracellular NAD/NADH ratio and induces protein deacetylatio...
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| Publicado no: | Innov Aging |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6183432/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.4436 |
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