Does p49/STRAP, a SRF-binding protein (SRFBP1), Modulate Cardiac Mitochondrial Function in Aging?

p49/STRAP (SRFBP1) is a transcriptional regulator that has been implicated in cardiac aging. p49/STRAP has a SRF binding domain and a BUD22 domain (which modulates cellular growth rate and cell size). We have observed that p49/STRAP alters the intracellular NAD/NADH ratio and induces protein deacety...

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發表在:Exp Gerontol
Main Authors: Zhang, Xiaomin, Williams, Emmanuel D., Azhar, Gohar, Rogers, Steven C., Wei, Jeanne Y.
格式: Artigo
語言:Inglês
出版: 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969173/
https://ncbi.nlm.nih.gov/pubmed/27337995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2016.06.008
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