THE EMERGING ANTIMICROBIAL PROTECTION HYPOTHESIS OF ALZHEIMER’S DISEASE

A considerable body of data suggests the beta-amyloid peptide (Abeta) plays a key role in Alzheimer’s disease (AD) pathology. The physiological role for Abeta has been unclear. We recently showed that synthetic Abeta has potent in vitro antimicrobial activity against CNS pathogens. We have since gen...

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發表在:Innov Aging
Main Authors: Moir, R.D., Vijaya Kumar, D., Choi, S., Tanzi, R.E.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6183144/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.4205
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