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Therapeutics for Alzheimer’s disease based on the metal hypothesis
Alzheimer’s disease is the most common form of dementia in the elderly, and it is characterized by elevated brain iron levels and accumulation of copper and zinc in cerebral β-amyloid deposits (e.g., senile plaques). Both ionic zinc and copper are able to accelerate the aggregation of Aβ, the princi...
Tallennettuna:
| Päätekijät: | , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Springer-Verlag
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518205/ https://ncbi.nlm.nih.gov/pubmed/18625454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nurt.2008.05.001 |
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