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SIRT1 facilitates amyloid beta peptide degradation by upregulating lysosome number in primary astrocytes
Previous studies have shown that sirtuin 1 (SIRT1) reduces the production of neuronal amyloid beta (Aβ) and inhibits the inflammatory response of glial cells, thereby generating a neuroprotective effect against Aβ neurotoxicity in animal models of Alzheimer's disease. However, the protective ef...
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| Publicado no: | Neural Regen Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Medknow Publications & Media Pvt Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6183050/ https://ncbi.nlm.nih.gov/pubmed/30233076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.239449 |
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