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Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system
BACKGROUND: Amyloid beta peptide (Aβ) is the main component of extraneuronal senile plaques typical of Alzheimer’s disease (AD) brains. Although Aβ is produced by normal neurons, it is shown to accumulate in large amounts within neuronal lysosomes in AD. We have recently shown that under normal cond...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3514139/ https://ncbi.nlm.nih.gov/pubmed/23210724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-9158-1-19 |
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