The novel amyloid-beta peptide aptamer inhibits intracellular amyloid-beta peptide toxicity

Amyloid β peptide binding alcohol dehydrogenase (ABAD) decoy peptide (DP) can competitively antagonize binding of amyloid β peptide to ABAD and inhibit the cytotoxic effects of amyloid β peptide. Based on peptide aptamers, the present study inserted ABAD-DP into the disulfide bond of human thioredox...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Xu, Yang, Yi, Jia, Mingyue, Ma, Chi, Wang, Mingyu, Che, Lihe, Yang, Yu, Wu, Jiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications & Media Pvt Ltd 2013
Schlagworte:
Research and Report Article: Neurodegenerative Disease and Neural Regeneration
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107502/
https://ncbi.nlm.nih.gov/pubmed/25206370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-5374.2013.01.005
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