Toll-like receptor 9 negatively regulates pancreatic islet beta cell growth and function in a mouse model of type 1 diabetes

AIMS/HYPOTHESIS: Innate immune effectors interact with the environment to contribute to the pathogenesis of the autoimmune disease, type 1 diabetes. Although recent studies have suggested that innate immune Toll-like receptors (TLRs) are involved in tissue development, little is known about the role...

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Udgivet i:Diabetologia
Main Authors: Liu, Mengju, Peng, Jian, Tai, Ningwen, Pearson, James A., Hu, Changyun, Guo, Junhua, Hou, Lin, Zhao, Hongyu, Wong, F. Susan, Wen, Li
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182661/
https://ncbi.nlm.nih.gov/pubmed/30094467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-018-4705-0
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