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Interferon-beta Inhibits Toll-Like Receptor 9 Processing in Multiple Sclerosis
BACKGROUND/OBJECTIVE: Viral infections have been implicated in the pathogenesis of multiple sclerosis (MS). Plasmacytoid dendritic cells (pDCs) are present in peripheral blood, cerebrospinal fluid and brain lesions of MS patients. PDCs sense viral DNA via Toll-like receptor 9 (TLR9) which has to be...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058378/ https://ncbi.nlm.nih.gov/pubmed/21061396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22136 |
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