Deregulation of secondary metabolism in a histone deacetylase mutant of Penicillium chrysogenum

The Pc21 g14570 gene of Penicillium chrysogenum encodes an ortholog of a class 2 histone deacetylase termed HdaA which may play a role in epigenetic regulation of secondary metabolism. Deletion of the hdaA gene induces a significant pleiotropic effect on the expression of a set of polyketide synthas...

Full description

Saved in:
Bibliographic Details
Published in:Microbiologyopen
Main Authors: Guzman‐Chavez, Fernando, Salo, Oleksandr, Samol, Marta, Ries, Marco, Kuipers, Jeroen, Bovenberg, Roel A. L., Vreeken, Rob J., Driessen, Arnold J. M.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182556/
https://ncbi.nlm.nih.gov/pubmed/29575742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.598
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items